SE Protects Your Patients

Features from CLEARFIL SE BOND

  • Virtually no post-operative sensitivity
  • Excellent bond strength for enamel and dentin
  • Fast and simple procedure with low technique sensitivity

Advanced New Features

  • Antibacterial cavity cleansing effect
  • Fluoride-releasing properties
  • Higher, more durable bond than CLEARFIL SE BOND

Advanced New Features for More Confidence

Antibacterial Cavity Cleansing Effect from MDPB

Studies show that the risk of bacteria remaining in a cavity tends to increase with the smaller, “minimal intervention” cavities1. Many doctors are using cavity cleansers, such as Consepsis (Ultradent) to address this tendency. CLEARFIL SE Protect contains a new functional monomer MDPB, which exhibits an “Antibacterial Cavity Cleansing Effect.” The antimicrobial effect with CLEARFIL SE Protect is greater than with current cavity cleansers as shown in Fig. 1, and is biologically safe because MDPB is fixed and will not leak after curing2. In addition, CLEARFIL SE Protect is a cost and time saver by eliminating extra steps.
Fig. 1 Number of Bacterial Recovery: Data from M. Türkün et al. Am. J. Dent., Vol. 19, 166-170, 2006. *Not a registered trademark of Kuraray Co., Ltd.
Fig. 2 The bactericidal mechanism of MDPB is presumed to be similar to the well-know antibacterial agent CPC**, which is in many toothpastes and mouth rinses. **Cetyl pyridinium chloride


CLEARFIL SE Protect contains a patented***, specially treated sodium fluoride (NaF); the NaF in CLEARFIL SE Protect is coated with a unique polymer capsule that allows release of the NaF while the bonding layer physical properties, including strength, are maintained.
CLEARFIL SE Protect makes an “acid-base resistant zone” (called Super Dentin) interface between the bond and dentin behind the hybrid layer
(Fig. 3, SEM image), as a result of the fluoride-release. Etch & rinse (total-etch) products like Adper Single Bond cannot make this zone3, 4.
This zone is 1.2µm which is thicker than the hybrid layer and very important for resisting the acid generated by bacteria if microleakage does occur3, 4.

Fig. 3 SEM image after soaking in a mild acid condition: Courtesy of G. Inoue, T. Nikaido and J. Tagami, Tokyo Medical and Dental University, Japan

Virtually No Post-Operative Sensitivity

Studies evaluating post-operative sensitivity of CLEARFIL SE Protect were published by Dr. Türkün, Ege Univ. School of Dentistry (Turkey) and THE DENTAL ADVISOR. The results reported that no postoperative sensitivity was experienced during one year5 and during 6 week6 evaluation period, respectively. The image in Fig. 4 was created using Transmission Electron Microscopy (TEM) technology. It clearly shows that CLEARFIL SE Protect bonds strongly to dentin. No gaps is a key factor in preventing post-operative sensitivity.

Superior Bond Strength and Durability

The test results of tensile bond strength (Fig. 5) show that CLEARFIL SE Protect has clear advantages regarding bond strength and durability compared with 3- or 2-step total-etch (etch and rinse) bonding agents, such as Adper Scotchbond Multi-Purpose* (3-step) or Adper Single Bond* (2-step), and 1-step self-etch such as i Bond*. In addition, CLEARFIL SE Protect showed excellent clinical performance in high stress bearing areas for at least five years7.
Fig. 4 TEM Micrograph: Courtesy of Dr. Hidehiko Sano, et al., Hokkaido Univ. Japan
Fig. 5 Tensile bond strength of adhesives to enamel and dentin. K.L. O’Keefe, V. Santiago-Doyle, L.M. Pinzon, J.M. Powers. J Dent Res 84: 2005 [Abstract 2970].
1) S. Imazato; Dent. Mater. J., 28(1), 11-19, 2009
2) E.A. Koulaouzidou et al.: J. Contep Dent. Pract., 9(7), 57-64, 2008
3) K. Waidyasekera, J. Tagami et al., J. Dent (37), 604-609, 2009
4) T. Nikaido, J. Tagami et al., Biomed Mater Eng. 2009;19(2-3):163-71
5) L. S. Türkün et al. JADA Vol. 136, 657-664 2005
6) The Dental Advisor, Vol. 21, No. 8, Oct. 2004
7) L. S. Türkün: J. Dent. Res. 2008, IADR abstract 0623
*** Patent number: US5908879


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